Even with medical advancements, emerging and re-emerging diseases—along with microbial adaptations and antimicrobial resistance—will continue to threaten healthcare. With uncertainty around what the next pandemic or outbreak will be, healthcare personnel (HCP) must stay vigilant to protective measures and follow transmission-based precautions to ensure patient safety. Understanding the risk factors that facilitate the transmission of infectious agents is important for preventing the spread of these microorganisms in various healthcare settings. In addition, recognizing risk factors can help HCP determine the need for additional interventions when patients colonized or infected with these microorganisms enter healthcare facilities. Understanding transmission risk factors will also help HCP understand healthcare-associated infection (HAI) surveillance data and develop and implement interventions to mitigate the transmission of infectious agents. Ref 21-1 Centers for Disease Control and Prevention (CDC). Isolation Precautions Guideline https://www.cdc.gov/infection-control/hcp/isolation-prec... - You do not have permission to view this object.  Ref 21-2 Weiner-Lastinger LM, Pattabiraman V, Konnor RY, et al. The impact of coronavirus disease 2019 (COVID-19) on healthcare-associated infectio... - You do not have permission to view this object.  Ref 21-3 Van Seventer JM, Hochberg NS. Principles of Infectious Diseases: Transmission, Diagnosis, Prevention, and Control. International Encyclope... - You do not have permission to view this object.